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Chromkit
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SiliaSep PREMIUM flash chromatography cartridges.

Supplied new and unopened as a SiliCycle reseller, not as an aftermarket equivalent. Chromkit invoices you in Canadian dollars and the goods ship inside Canada, so there is no customs entry and no exchange rate on your side. Certificates and technical documentation come with the order. If you want to compare this against the sorbent you run now, ask and I will arrange samples before you commit a method to it.

Flash and preparative columns

SiliaSep PREMIUM Flash Cartridges, Silica-Based, C18 Monomeric

Monomeric C18 on 25 micron spherical silica, the reversed phase cartridge for a purification that needs resolution the standard 40 to 63 micron grade will not give. Worth the cost when the impurity sits close to the product and a repeat run on standard silica has already failed, and hard to justify when it does not. Confirm your system runs aqueous mobile phase and that the cartridge fitting matches before ordering.

Sorbent
C18 Monomeric
Product line
SiliaSep PREMIUM Flash Cartridges, Silica-Based
Particle size
25 µm
Pore size
90 Å
Condition
new
Price
from CA$93 before tax and shipping. Confirmed on the quote.

Available formats 10 part numbers

Part number Format Per box Price
FLH-03295D-A-ISO04 4 g 2 CA$93
FLH-03295D-A-ISO04-B 4 g 10 CA$369
FLH-03295D-A-ISO12 12 g 1 CA$138
FLH-03295D-A-ISO12-B 12 g 10 CA$1,172
FLH-03295D-A-ISO25 25 g 1 CA$228
FLH-03295D-A-ISO25-B 25 g 10 CA$1,937
FLH-03295D-A-ISO40 40 g 1 CA$256
FLH-03295D-A-ISO40-B 40 g 5 CA$1,087
FLH-03295D-A-ISO80 80 g 1 CA$525
FLH-03295D-A-ISO80-B 80 g 5 CA$2,229

Quote the part number, or tell me the sample and volume and I will tell you which size to run. Prices are per box, before tax and shipping.

Request a quote +1 647-919-3041

Before you order: if the instrument is misbehaving, tell me the symptom, not the part number. Lamps and seals get replaced for problems they did not cause. The first look costs nothing, and if this part is not the fix, I will say so.

How buying works, written for procurement →

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A water wettable polymer, so the bed does not dewet if the cartridge runs dry. That is the commonest reason a silica C18 extraction loses recovery halfway through a batch, and it is the single practical argument for a polymeric sorbent. HLB retains acids, bases and neutrals together, so it is the first choice when you are screening or when the analyte list is mixed. That breadth is also its limit. It holds matrix as readily as it holds analyte, so if you are fighting ion suppression in LC-MS, an ion exchange or mixed mode sorbent will give you a cleaner extract than this one.

Sorbent
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Product line
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Particle size
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Strong anion exchange on a polymer backing. The exchange sites stay charged across the working pH range, so retention of an acidic analyte does not drift with load pH the way it can on a weak exchanger. Use it when reversed phase alone leaves the extract too dirty and the analyte carries a negative charge you can work with. It will not hold neutrals or bases. If your analyte list is mixed, run HLB, or run this as a second step after a reversed phase cleanup.

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SiliaPrepX SPE Cartridges, Polymer-Based, SCX

Strong cation exchange on a polymer backing, for basic analytes. Load at a pH where the base is protonated and it is held by charge rather than by hydrophobicity, which means you can wash with organic solvent hard enough to strip most of the matrix without losing the analyte. Elution needs base in the solvent. It will not retain acids or neutrals, and for a permanently charged base such as a quaternary amine it can hold too well to elute cleanly, which is what the weak exchanger is for.

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Product line
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Particle size
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Weak cation exchange, a carboxylic acid on a polymer. It exists for the analytes that strong cation exchange holds too tightly. A quaternary amine or another permanently charged base comes off a weak exchanger with a change of pH instead of a harsh solvent, so recovery improves and the extract stays cleaner. For a weakly basic analyte it does the opposite and barely retains at all. Check the pKa of your compound before choosing between this and the strong exchanger.

Sorbent
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Product line
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Alternative to
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Particle size
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